Dr. Shery Jacob

Professor of Pharmaceutics

Education

  • B.Pharm from Mangalore University, India in 1992
  • M.Pharm in Pharmaceutics from Birla Institute of Technology, India in 1997
  • Ph.D. in Pharmaceutics from Manipal Academy of Higher Education, India in 2006
  • Post-Doctoral Fellowship in bioengineering from Clemson University, South Carolina, USA in 2008.

Research Interest

  • Pharmaceutical pre-formulation and material characterization
  • Solubility enhancement technologies
  • Nanotechnology in drug delivery

Selected Publications

  • Satyavert, Gupta, S., Choudhury, H., Jacob, S., Nair, A., Dhanawat, M., & Munjal, K. (2021). Pharmacokinetics and tissue distribution of hydrazinocurcumin in rats. Pharmacological Reports. doi: 10.1007/s43440-021-00312-5. [link]
  • Nair, A.B., Shah, J., Jacob, S., Al-Dhubiab, B.E., Patel, V., Sreeharsha, N., Shinu, P. Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation. Pharmaceutics 202113, 728. [link]
  • Chaudhary, S., Nair, A.B., Shah, J. Gorain, B., Jacob, S., Shah, H., Patel, V. Enhanced Solubility and Bioavailability of Dolutegravir by Solid Dispersion Method: In Vitro and In Vivo Evaluation—a Potential Approach for HIV Therapy. AAPS PharmSciTech 22, 127 (2021). [link]
  • Nair. A.B., Shah. J., Al-Dhubiab. B.E., Jacob. S., Patel. S.S., Venugopala. K.N., Morsy. M.A., Gupta. S., Attimarad. M., Sreeharsha. N., Shinu. P. Clarithromycin Solid Lipid Nanoparticles for Topical Ocular Therapy: Optimization, Evaluation and In Vivo studies. Pharmaceutics 2021, 13, 523. [link]
  • Nair. A.B., Shah. J., Jacob. S., Al-Dhubiab. B.E., Sreeharsha. N., Morsy. M.A., et al. (2021) Experimental design, formulation and in vivo evaluation of a novel topical in situ gel system to treat ocular infections. PLoS ONE 16(3): e0248857. [link]
  • Shah. H., Nair. A.B., Shah. J., Jacob. S., Bharadia. P., Haroun. M. “Proniosomal vesicles as an effective strategy to optimize naproxen transdermal delivery’’. Journal of Drug Delivery Science and Technology. 2021, 63,102479. [link]
  • Jacob, S., Nair, A.B., Shah, J., Sreeharsha, N., Gupta, S., Shinu, P. Emerging Role of Hydrogels in Drug Delivery Systems, Tissue Engineering, and Wound Management. Pharmaceutics 2021, 13, 357. [link]
  • Jacob, S., Nair, A.B., Patel, V., Shah, J. 3D Printing Technologies: Recent Development and Emerging Applications in Various Drug Delivery Systems. AAPS PharmSciTech 21, 220 (2020). [link]
  • Shehata,T.M., Nair,A.B., Al-Dhubiab,B.E., Shah,J., Jacob,S., Alhaider,I.A., Attimarad, M., Elsewedy,H.S., Ibrahim,M.M. Vesicular emulgel based system for transdermal delivery of insulin: Factorial design and in vivo evaluation. Applied Sciences (2020). [link]
  • Jhaveri, M.; Nair, A.B.; Shah, J.; Jacob, S.; Patel, V.; Mehta,T. Improvement of oral bioavailability of carvedilol by liquisolid compact: optimization and pharmacokinetic studyDrug Delivery and Translational Research. (March 2020). [Link]
  • Jacob, S., Nair, A.B. & Shah, J. Emerging role of nanosuspensions in drug delivery systems. Biomater Res 24, 3 (2020). [Link]
  • Nair, A.B.; Shah, J.; Al-Dhubiab, B.E.; Patel, S.S.; Morsy, M.A.; Patel, V.; Chavda, V.; Jacob, S.; Sreeharsha, N.; Shinu, P.; Attimarad, M.; Venugopala, K.N. Development of Asialoglycoprotein Receptor-Targeted Nanoparticles for Selective Delivery of Gemcitabine to Hepatocellular Carcinoma. Molecules (2019), 24, 4566. [Link]
  • Nair,  A.B.,  Al-Dhubiab,  B.E.,  Shah,  J.,  Jacob,  S.,  Vismay,  S.,  Attimarad,  M., SreeHarsha,  N.,  Akrawi,  S.H.,  Shehata,  T.M.,  Mucoadhesive  buccal  film  of  almotriptan  improved  therapeuticdelivery in rabbit model, Saudi Pharmaceutical Journal (2019). [Link]
  • Nair, A.B., Shah, J., Aljaeid, B.M., Al‐Dhubiab, B.E., Jacob, S. (2019). Gellan Gum‐Based Hydrogel for the Transdermal Delivery of Nebivolol: Optimization and EvaluationPolymers, 11(10), 1699. [Link]
  • Jacob S, Nair AB, Shah J (2019). Revisiting clinical practice in therapeutic drug monitoring of first-generation antiepileptic drugs. Drugs & Therapy Perspectives. 1-8. [Link]
  • Nair, A.B., Gupta, S., Al-Dhubiab, B.E., Jacob, S., Shinu, P., Shah, J., Morsy, M.A., SreeHarsha, N., Attimarad, M., Venugopala, K.N., Akrawi, S.H (2019). Effective Therapeutic Delivery and Bioavailability Enhancement of Pioglitazone Using Drug in Adhesive Transdermal Patch. Pharmaceutics. 11, 359. [Link]
  • Jigar, S., Nair, A. B., Hiral, S., Jacob, S., Shehata, T. M., & Morsy, M. A. (2019). Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel. Asian Journal of Pharmaceutical Sciences. [Link]
  • Shah, J., Nair, A.B., Jacob, S., Patel,R.K.,Shah,H.,Shehata,T.M.,Morsy, M.A. (2019).  Nanoemulsion Based Vehicle for Effective Ocular Delivery of Moxifloxacin Using Experimental Design and  Pharmacokinetic Study in RabbitsPharmaceutics 2019, 11(5), 230. [Link]
  • Jacob, S., Nair, A.B., Morsy M.A. (2018).  Dose translation between laboratory animals and human in preclinical and clinical phases of drug developmentDrug Development and Research, 21 October 2018. [Link]
  • Jacob, S., Nair, A.B. (2018).  Cyclodextrin complexes: Perspective from drug delivery and formulationDrug Development and Research, 79(5), 201-217. [Link]
  • Jacob, S., Morsy M.A., Nair, A.B. (2018).  An overview on the insulin preparations and devicesIndian Journal of Pharmaceutical Education and Research, 52(4), 550-557 [Link]
  • Jacob,S.,Nair,A.B.(2018). An updated overview with simple and practical approach for developing in vitro–in vivo correlation. Drug Development Research, 1-14 [Link]
  • Jacob, S., & Nair, A. B. (2017). A review on therapeutic drug monitoring of the mTOR class of immunosuppressants: everolimus and sirolimus. Drugs & Therapy Perspectives, 1-12. [Link]
  • Jacob, S., & Nair, A. B. (2016). An updated overview on therapeutic drug monitoring of recent antiepileptic drugs. Drugs in R&D, 1-14. [Link]
  • Jacob, S., Nair, A. B., & Al-Dhubiab, B. E. (2016). Preparation and evaluation of niosome gel containing acyclovir for enhanced dermal deposition. Journal of liposome research, 1-10.
  • Jacob, S. & Nair, A. B. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27. [Link]
  • Jacob, S., Shirwaikar, A., Anoop, S., Khaled, R., Imtiaz, M., & Nair, A. (2016). Acid neutralization capacity and cost-effectiveness of antacids sold in various retail pharmacies in the United Arab Emirates. Hamdan Medical Journal, 9(2), 137
  • Jacob, S., Tambawel, J., Trooshi, F. M., & Alkhoury, Y. (2013). Consumption pattern of nutritional health drinks and energy drinks among university students in Ajman, UAE. Gulf Medical Journal, 2(1), 22. [Link]
  • Nair, A., Jacob, S., Al-Dhubiab, B., Attimarad, M., & Harsha, S. (2013). Basic considerations in the dermatokinetics of topical formulations. Brazilian Journal of Pharmaceutical Sciences, 49(3), 423. [Link]
  • Jacob,S, Gupta, R., Kumria, R., Nair, A. B., & Attimarad, M. (2010). Formulation and evaluation of enteric coated tablets of proton pump inhibitor. Journal of Basic and Clinical Pharmacy, 1(4), 215. [Link]
  • Jacob,S., Nair, A. & Reddy, C.(2009). Delivery of a classical antihypertensive agent through the skin by chemical enhancers and iontophoresis. Skin Research and Technology, 15(2), 187. [Link]
  • Jacob, S., Shirwaikar, A., & Nair, A. (2009). Preparation and evaluation of fast-disintegrating effervescent tablets of glibenclamide. Drug Development and Industrial Pharmacy, 35(3), 321. [Link]