Head of Department of Pharmaceutical Sciences and Assistant Professor of Medicinal Chemistry
Ph.D. in Chemistry (Organic Chemistry major and Biochemistry minor), Wayne State University, Detroit, MI, USA, 2017
Dr. Ahmed Thabet Negmeldin
Publications:
- Elkhalifa, D., Rayan, M., Negmeldin, A.T., Elhissi, A., & Khalil, A. (2022). Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases. Biomedicine & Pharmacotherapy, 145, 112385. doi: 10.1016/j.biopha.2021.112385.
- Joseph Naguib, M., Moustafa Kamel, A., Thabet Negmeldin, A., Elshafeey, A. H., & Elsayed, I. (2020). Molecular docking and statistical optimization of taurocholate-stabilized galactose anchored bilosomes for the enhancement of sofosbuvir absorption and hepatic relative targeting efficiency. Drug Delivery, 27(1), 996-1009. [Link]
- AbdelHamid, MK, Labib, MB, Negmeldin, AT, Al-Shorbagy, M, and Mohammed MR (2018). Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinoma as VEGFR-2 Inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 33(1), 1472-1493. [Link]
- Negmeldin, AT, Knoff, JR, and Pflum, MKH (2018). The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity. European Journal of Medicinal Chemistry, 143, 1790-1806. [Link]
- Negmeldin, AT, Padige, G, Bieliauskas, AV, and Pflum, MKH (2017). Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity. ACS Medicinal Chemistry Letters, 8(3), 281–286. [Link]